We understand that some of these may be difficult to stop. If you have concerns about stopping any of the following medications please discuss this with your physician’s office and let us know. Chloroquine vs hydroxychloroquine Plaquenil induced psoriasis Plaquenil and risperidone Plaquenil and hemolytic anemia Because Plaquenil is the kind of drug that builds up in the blood stream and tissues I suspect, it has a very long half life. Simple drugs like abx can take as much as a month to completely clear from the body. So the Plaquenil could hang around for a while. Carry the Benadryl with you. I use the children's liquid because it goes to work faster. May 26, 2014 can you take hydroxychloroquine and antihistamine No, you don't want to take two of the same medications. If the Zyrtec is not taking care of your allergies, don't take a second antihistamine on. Drug interactions are reported among people who take Zyrtec and Plaquenil together. This study is created by eHealthMe based on reports of 826 people who take Zyrtec and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from millions of FDA reports. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Can i take benadryl with plaquenil Can you take hydroxychloroquine with, Can you take hydroxychloroquine with antihistamine - Answers Plaquenil medicine side effects For tamoxifen to do its job, it needs to be broken down in the body by a key protein known as CYP2D6. Unfortunately, many common medicines can block or slow down CYP2D6, and that would make tamoxifen less effective. Certain medications used to treat depression should be avoided by women taking tamoxifen. Drugs to Avoid for Women Taking Tamoxifen - Stop Cancer Fund. Zyrtec and Plaquenil drug interactions - eHealthMe. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. I've been taking a Benadryl at night to help but I don't take anything during the day cause I work and need to be alert. I am wondering if this is a common side effect? I am going to lower my dose back down to once a day until I can talk to my doctor but I thought I'd check in and see if it's normal or if I should worry more? Severe Interactions These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Chiu on can benadryl improve lupus symptoms Antihistamines block the receptor sites for histamine released from mast cells or basophils in allergic reactions. As such they suppress symptoms to a variable amount. The only present treatment that can actually alter the allergic condition diathesis is immunotherapy.