Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Plaquenil toxicity visual field What tier is plaquenil Since the initial success of the treatment of lupus erythematosus with quinacrine Atabrine by Prokoptchouk1a and Popoff and Kutinscheff1b and later by Page,2 in Europe, attempts have been made to find other less toxic antimalarial agents. Numerous investigators3 in this country also have had good. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus. Systemic lupus erythematosus is a disease that continues to evolve over time. Thus, a patient who presents with skin and joint disease remains at risk for renal disease even after having lupus. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Chloroquine for discoid lupus Discoid Lupus Erythematosus Medication Antimalarial agents., Chloroquine Nivaquine, Resochin Healing Is Divine Antimicrobial drugs Plaquenil medicine side effectsPlaquenil mycoplasmaPlaquenil davis A trial conducted in 1953 investigated the effects of Chloroquine Aralen treatment on 30 people with discoid lupus. Researchers concluded that treatment with Chloroquine furnished significant improvement in early cases of dermatological lupus symptoms. Side effects Most people do not experience side effects from taking Aralen. Aralen Chloroquine MyLupusTeam. Treatment of Systemic Lupus Erythematosus An Update - American Family.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. In active rheumatoid arthritis and systemic and discoid lupus erythematosus, to avoid excessive dosage in obese patients, the daily maximum dose should be calculated on the basis of ideal body weight. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus.