Chloroquine for discoid lupus

Discussion in 'Canada Drug' started by sergeiiii1, 29-Feb-2020.

  1. michail Moderator

    Chloroquine for discoid lupus


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

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    Since the initial success of the treatment of lupus erythematosus with quinacrine Atabrine by Prokoptchouk1a and Popoff and Kutinscheff1b and later by Page,2 in Europe, attempts have been made to find other less toxic antimalarial agents. Numerous investigators3 in this country also have had good. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus. Systemic lupus erythematosus is a disease that continues to evolve over time. Thus, a patient who presents with skin and joint disease remains at risk for renal disease even after having lupus.

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Chloroquine for discoid lupus

    Discoid Lupus Erythematosus Medication Antimalarial agents., Chloroquine Nivaquine, Resochin Healing Is Divine Antimicrobial drugs

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  5. A trial conducted in 1953 investigated the effects of Chloroquine Aralen treatment on 30 people with discoid lupus. Researchers concluded that treatment with Chloroquine furnished significant improvement in early cases of dermatological lupus symptoms. Side effects Most people do not experience side effects from taking Aralen.

    • Aralen Chloroquine MyLupusTeam.
    • Treatment of Systemic Lupus Erythematosus An Update - American Family..
    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins..

    Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. In active rheumatoid arthritis and systemic and discoid lupus erythematosus, to avoid excessive dosage in obese patients, the daily maximum dose should be calculated on the basis of ideal body weight. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus. Chloroquine nivaquine is an antimalarial drug used in the treatment and prophylaxis of uncomplicated malaria, extraintestinal amebiasis and discoid lupus.

     
  6. 555 XenForo Moderator

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term - Lupus Do you still have joint and muscle pain on plaquenil? Joint Pain Johns Hopkins Sjögren’s Center
     
  7. Coffin New Member

    Aralen, Chloroquine phosphate chloroquine dosing. Malaria. Prevention 500 mg 300 mg base PO once/week. Non-chloroquine-resistant. 1 g 600 mg base PO, THEN; 500 mg 300 mg base PO 6-8 hours later, THEN; 500 mg 300 mg base PO at 24 hours & 48 hours after initial dose; Amebiasis, Extraintestinal. 1 g 600 mg base PO qDay for 2 days, THEN. 500 mg 300 mg base qDay for 14-21 days

    CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria