Chloroquine phosphate drug study

Discussion in 'Canada Drugs' started by Denniss, 11-Mar-2020.

  1. Maliby11 Moderator

    Chloroquine phosphate drug study


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    For example, if you need to treat a 10 gallon aquarium with chloroquine at 10 mg/l, you would need to add 376 mg of the drug to the tank, a very small amount to try and weigh out. If you can more easily weigh out a single gram a nice round amount, you can dissolve that into 12 teaspoons of distilled water. Latest coronavirus drug research indicates that based on early results from clinical trials by Chinese researchers, Chloroquine Phosphate, an antimalarial drug, has a certain curative effects on the novel coronavirus disease COVID-19. Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine phosphate drug study

    Aquarium Fish Chloroquine A "New" Drug for Treating Fish Diseases., Latest On Coronavirus Drug Research Chloroquine Another.

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  6. The dosage of Chloroquine phosphate is often expressed in terms of equivalent Chloroquine base. Each 500 mg tablet of Chloroquine phosphate contains the equivalent of 300 mg Chloroquine base. In infants and children the dosage is preferably calculated by body weight.

    • Chloroquine - Prescription Drug Information..
    • Aralen, Chloroquine phosphate chloroquine dosing, indications..
    • Chloroquine Phosphate - WebMD.

    The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light. Chloroquine phosphate, an antimalarial drug, is shown to have yielded positive data against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. It is slated to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health. Encouraging news a new medical study shows a commonly available anti-malaria drug known as chloroquine aka chloroquine phosphate is showing strong results against COVID-19 infections in both China and South Korea.

     
  7. neur0.Ice Guest

    Download PDF Many systemic medications may cause retinal toxicity. Chloroquine retinopathy - Wikipedia Hydroxychloroquine Plaquenil Toxicity and Recommendations. Plaquenil Toxicity - Symptoms, Treatment, Risk Factors.
     
  8. v0v Guest

    Description: An exception occurred while processing your request. Hydroxychloroquine and Chloroquine Retinopathy. Despite Plaquenil dosing recommendations, retinal toxicity remains My Take on New Ocular Screening Guidelines for Plaquenil RheumNow.
     
  9. Darid Moderator

    Osteo Bi-Flex Triple Strength Side Effects Common, Severe, Long Term. Note This document contains side effect information about chondroitin / glucosamine. Some of the dosage forms listed on this page may not apply to the brand name Osteo Bi-Flex Triple Strength.

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  10. lomtev New Member

    Hydroxychloroquine Indications, Side Effects, Warnings. Take hydroxychloroquine with food or milk. Swallow whole. Do not chew, break, or crush. Keep taking hydroxychloroquine as you have been told by your doctor or other health care provider, even if you feel well. Do not take antacids or kaolin within 4 hours of hydroxychloroquine. What do I do if I miss a dose?

    Hydroxychloroquine Oral Uses, Side Effects, Interactions.