Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Retinal thinning in plaquenil toxicity Can i use of hydroxychloroquine with sulfur allergy Chloroquine resistance blood stage inhibition The dapsone treatment gave excellent results in 8 patients 24%, some effect in 8 patients 24%, while no response was seen in 17 patients 52%. Of the patients who had earlier been treated with hydroxychloroquine HCQ, 76% responded excellently to the treatment. Of 6 patients who received a combined dapsone and HCQ therapy, 2 responded well. Hydroxychloroquine Hydroxychloroquine, an antimalarial, exerts disease-modifying anti-rheumatoid effects by interfering with the binding of complement to immune complexes. Hydroxychloroquine is administered at a rate of ∼400 mg/day for 4-12 weeks until therapeutic levels are attained, after which the dose is decreased by approximately one-half. Consider it only after failure of antihistamines, indomethacin, colchicine, dapsone, or hydroxychloroquine. Its effect on urticarial vasculitis likely is mediated by its anti-inflammatory effect. This class of medications decreases capillary permeability and inhibits the mitotic rate of lymphocytes. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Dapsone hydroxychloroquine Plaquenil and Dapsone drug interactions - eHealthMe, Hydroxychloroquine - an overview ScienceDirect Topics Chloroquine phosphate api manufacturers indiaCan plaquenil cause drusenLong-term effects of taking plaquenilPlaquenil retinal damageHydroxychloroquine in lupus nephritis Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Urticarial Vasculitis Medication Antihistamines, Anti.. Dapsone Aczone - Side Effects, Dosage, Interactions - Drugs. Dapsone can be used in CU in doses of 50-100 mg/day. In 2013, a double-blind placebo controlled trial n = 22 of antihistamine-refractory chronic urticaria reported a statistically significant improvement in itch, hive, and VAS scores in patients treated with dapsone as compared to placebo. Do not take the following medications with dapsone – trimethoprim, probenicid, pyrimethamine, rifamipicin, sulphonamides and hydroxychloroquine – unless this has been specifically discussed with your doctor. What monitoring is required? Initially several baseline blood tests will be performed to make sure there are no underlying problems. Dapsone is a sulfone antimicrobial agent. Sulfasalazine is an anti-inflammatory 5-aminosalicylic acid 5-ASA derivative. The author prefers dapsone over sulfasalazine but prefers sulfasalazine for patients with underlying anemia. Both dapsone and sulfasalazine can be combined with hydroxychloroquine. See 'Combined with a sulfone' below.