Listing a study does not mean it has been evaluated by the U. Most of cases are expressed as a mild disease, with intense fever and arthralgias, with rare but serious complications (encephalitis, liver, cardiac or renal failures.) having required a hospitalization in an intensive care unit. A severe outbreak of Chikungunya fever has been reported at La Réunion Island (France) in 2005-2006. Chikungunya virus is an alphavirus transmitted to humans by the bite of infected mosquitoes, usually of the genus Aedes (Aedes albopictus in La Réunion). Chloroquine pancreatic cancer Lupus remission and plaquenil Plaquenil solar urticaria Aug 01, 2009 Until now, neither specific treatment nor prophylaxis have been available for Chikungunya fever. The goal of Couderc et al in an article published in this issue of the Journal was to find a specific treatment and prophylaxis for severe CHIKV infection during outbreaks. What are the bases for and the results of the Couderc et al study. For. The science behind chloroquine. First developed in the 1940s, chloroquine earned FDA approval as a malaria treatment in 1949 and long stood as the go-to treatment for the disease, according to. It is true that chloroquine displays antiviral and anti-inflammatory properties that, in our opinion, merit testing in the clinical management of some viral diseases. However, we reported no data on chikungunya, nor did we mention this disease in our articles in The Lancet Infectious Diseases. Chikungunya was proven in 246 serious cases; 101 patients had comorbidities, and 27% of confirmed cases eventually died. 273 of such serious cases (immediately life threatening condition) have been reported among the cases, in patients aged over 10 days (59% were 65 age old). Chikungunya disease and chloroquine treatment On Chikungunya Acute Infection and Chloroquine Treatment., Could the anti-malarial drug chloroquine treat COVID-19. Plaquenil and sclerodermaOct images of plaquenil toxicity In an open labeled pilot trial n=20 that was published 25 years ago, Brighton reported the efficacy of chloroquine phosphate 250 mg/day in the treatment of patients with chronic Chikungunya arthritis. Of the 10 patients who completed 20 weeks of therapy, Ritchie articular index and morning stiffness improved significantly. EPIDEMIOLOGY, CLINICAL MANIFESTATIONS, AND DIAGNOSIS OF.. On the use of chloroquine for chikungunya - The Lancet.. Chikungunya Disease and Chloroquine Treatment. Chikungunya disease and chloroquine treatment. Ilenia Delogu. Unité des Virus Emergents, UMR190 Aix‐Marseille 2 University‐IRD‐EHESP, Marseille, France. On the use of chloroquine for Chikungunya Article PDF Available in The Lancet Infectious Diseases 710633 November 2007 with 274 Reads How we measure 'reads' Chloroquine is also utilised in the treatment of autoimmune diseases. Yet the activity of the molecule is not limited to malaria and the control of inflammatory processes, as illustrated by its broad-spectrum activity against a range of bacterial, fungal and viral infections.