Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. H-chloroquine Plaquenil thrombocytopenia PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil side effects anti depressants Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings., Plaquenil Hydroxychloroquine Side effects, Images, Uses. Chloroquine to treat gbmChloroquine phosphate adverse effectsCan i take plaquenil if allergic to sulfa If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. Long-Term Side Effects of Plaquenil for Rheumatoid.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Anxiety and Plaquenil. On a whim, I did a search for plaquenil and anxiety. I was shocked to see that anxiety is a side effect. Maybe I'm not crazy after all. Talk to your doctor, pharmacist or other trusted healthcare provider. Describe your side effects in detail, as well as your family history of mental illness. If Serotonin Syndrome is suspected, the recommendation would be to discontinue SSRIs and start a different type of antidepressant that does not have an effect on serotonin. When cut, too much of the drug can be released at once and cause a reaction or side effects. When prescribed 300 mg. daily, you should alternate one tablet one day with two the next. I've been on Plaquenil for almost four years now and it's helped me a lot.