One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Plaquenil drug interactions side effects Mefloquine lariam and chloroquine From what I understand it is very rare for someone to have an allergic reaction to the Plaquenil and when they do that isn't how it shows up. Hopefull it's not the Plaquenil because this drug is really a very good drug for Lupus. I went through some paperwork I had about Plaquenil and am pasting it here for you to read. Dry macular degeneration is caused by cell function decline in the center of the retina, resulting in blurred vision. Yellow deposits, called Drusen, appear in the macula. If the drusen continue to grow, it can cause tissue in the macula to become damaged and die. Wet Macular degeneration is the growth of abnormal blood vessels behind the macula. Aug 14, 2017 According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Can plaquenil cause drusen Plaquenil Side Effects Common, Severe, Long Term -, Macular Degeneration Symptoms, Causes, Treatment, and. Plaquenil maculopathy rateWeight gain with plaquenilOrder aralen prescribing The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g. Patients with renal or hepatic dysfunction are at an increased risk of toxicity. 1 Other risk factors for retinal toxicity include short stature, obesity. Pause the Plaquenil?. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. What Causes Age-Related Macular Degeneration?. May 16, 2011 Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists. Check with your doctor as soon as possible if any of the following side effects occur blurred vision or any change in vision – this effect may also occur or worsen after stopping the medication. change in colour of hair or skin pigment. flu-like symptoms sudden lack of energy, fever, cough, sore throat The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied, no. I don't need to be dilated because I don't have macular degeneration.