Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and ovarian cancer Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine Plaquenil coffee Methotrexate sulfasalazine hydroxychloroquine and leflunomide Plaqunil helped me a lot but the side effects are horrible. I have had depression with nervousness and suicidal thoughts. My skin exfoliates in sheets. My muscles are weakened and I have problems urinating. I am withdrawing from this drug and I had panic attacks and my heart is racing. My hair is okay but this medicine side effects are bad. View detailed reports from patients taking plaquenil who experienced heart rate increased. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Find information about common, infrequent and rare side effects of Gabapentin Oral. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and suicidal thoughts Anyone on Mycophenolate Cellcept? DailyStrength, Hydroxychloroquine Sulfate Heart Rate Increased Reports. Plaquenil during pregnancy categoryPlaquenil missed period Apr 27, 2015 Thank you everyone for the kind words i really neede that you guys are awesome sorru from philly we say you guys lol chappelle can u please share with me what you have used for bartonella i am only on ceftin tried doxy plaquenil suicidal thoughts dont know which one caused it can u please tell me what worked for you.thankyou Suicidal -. Common and Rare Side Effects for Gabapentin Oral. Depression Increases Suicide Risk in RA Patients.. Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Recurrent thoughts of death or suicide; Clinical depression may not be recognized in people with lupus because its symptoms and the symptoms of active lupus can be so similar. For example, lack of energy, trouble sleeping, and diminished sexual interest can be attributed to the lupus itself. However, these are also symptoms of clinical depression. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood.