Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Does hydroxychloroquine cause loss of taste in mouth How do plaquenil look Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. Chloroquine and its analogue hydroxychloroquine are used as disease-modifying antirheumatic drugs in autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Ocular manifestations of toxicity include whorl-pattern epithelial keratopathy, subcapsular cataracts, retinopathy, optic atrophy, paralysis of accommodation, and extraocular muscle palsy. 1 Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists and ophthalmologists. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Chloroquine retinopathy Chloroquine Retinopathy - ScienceDirect, Chloroquine Retinopathy Nephrology JAMA Ophthalmology JAMA Network Chloroquine autophagy inducerChloroquine sensitive areasPlaquenil blurry eyes from allergies Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus eye toxicity limits long-term use of the drugs. Chloroquine retinopathy - Wikipedia. Hydroxychloroquine Retinopathy Still Alive and Well - The.. Hydroxychloroquine and Chloroquine Retinopathy Recommendations on.. Uploaded on Oct 30, 2015. Last modified by Caroline Bozell on Oct 30, 2015.; Rating Appears in Chloroquine Retinopathy Condition/keywords retinopathy, chloroquine Retinopathy, maculopathy, irreversible retinal damage, as well as macular degeneration have been reported. Retinopathy from chloroquine may be dose related. Initial and periodic eye examinations are recommended during prolonged treatment. Chloroquine should be discontinued immediately if there are changes in vision. Oct 01, 2018 Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base. Inactive Ingredients colloidal silicon dioxide, dibasic calcium phosphate, hydroxypropylmethylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate80, pregelatinized starch.