Long term use of plaquenil

Discussion in 'North West Pharmacy Canada' started by dniser, 14-Mar-2020.

  1. ofolfa Well-Known Member

    Long term use of plaquenil


    Please review the following URL and make sure that it is spelled correctly. Plaquenil is the brand name for the prescription drug hydroxychloroquine.

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    Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Focus on Eyes Long-term Plaquenil intake can affect your vision. Taking high doses or long-term treatment of Plaquenil, an anti-malaria drug used to treat lupus, can lead to vision problems.

    Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others.

    Long term use of plaquenil

    Hydroxychloroquine Side Effects, Dosage, Uses, and More, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses

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  5. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more.

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    Hydroxychloroquine is often prescribed as long-term therapy for many dermatologic indications, and it may have broader benefits e.g. preventing or improving thrombophilia associated with lupus erythematosus, neonatal lupus erythematosus, diabetes in rheumatoid arthritis and other connective tissue diseases, and as adjunctive therapy in some cancers. Long-term studies in animals have not been conducted to evaluate the carcinogenic potential of PLAQUENIL. The mutagenic potential of hydroxychloroquine was not evaluated. However, chloroquine has been shown to be a catalytic inhibitor of DNA repair enzymes topoisomerase II and to produce weak genotoxic effects through this mode of action. Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Although it has been shown that discontinuation of treatment with hydroxychloroquine is associated with exacerbation of SLE, long term maintenance rates of treatment with hydroxychloroquine in patients with SLE have not been investigated.

     
  6. MerenOK Guest

    Some people, especially children, recover completely, while others experience greatly diminished symptoms for long periods of time. Hydroxychloroquine staves off dermatomyositis symptoms. Taking Plaquenil for Rheumatoid Arthritis Dermatomyositis - Diagnosis and treatment - Mayo Clinic
     
  7. clis.ru Guest

    Pregnancy and Plaquenil - HealthBoards Hi, I'm new to posting here. I have lupus, and I had my daughter in Feb. 05. I have never taken plaquenil as I have a seizure disorder as well, however, I do know that my Rheumy told me that the only safe drug to take during pregnancy is prednisone.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More