Oct appearance of plaquenil toxicity

Discussion in 'Plaquenil' started by Ihty, 01-Mar-2020.

  1. nofollow XenForo Moderator

    Oct appearance of plaquenil toxicity


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Symptoms of Plaquenil toxicity are similar to other macular problems and may include Decreased fine vision or difficulty reading. Changes in Color vision. Missing Spots or shadows near the center of the vision. OCT scan top of normal macula compared to Plaquenil Toxicity bottom with loss of the outer retinal tissue around the macular center red boxes View more retina images at Retina Rocks, the world’s largest online multimedia retina image library and bibliography repository. Plaquenil toxicity first affects small areas of the retina between 5° and 15° from the fovea. Figures 2 and 3 show three patients at different stages of toxicity. Figure 2 bottom right shows a color display of normal mfERGs. The amplitude of the mathematically derived b-wave of the mfERG is displayed in a color scale.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Oct appearance of plaquenil toxicity

    Multimodal Imaging in Plaquenil Toxicity, Plaquenil Toxicity - Bennett & Bloom Eye Centers

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  7. Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure.

    • The Risk of Retinal Toxicity with Plaquenil - Sjogren's.
    • Retina Today - Evaluating Hydroxychloroquine Toxicity With Multifocal..
    • Hydroxychloroquine Plaquenil Toxicity and Recommendations..

    Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful.

     
  8. homepagekz New Member

    Take this medicine exactly as directed by your doctor. Chloroquine Phosphate - Fish Medication Information. Chloroquine Phosphate Bulk Uses, Side Effects. Chloroquine Phosphate - WebMD
     
  9. Philosopher_ XenForo Moderator

    Sjogren's syndrome can be difficult to diagnose because the signs and symptoms vary from person to person and can be similar to those caused by other diseases. Sjogren's Syndrome & Dry Mouth - Symptoms & Treatment OraCoat Study Raises Questions about Sjogren's and Plaquenil The Risk of Retinal Toxicity with Plaquenil - Sjogren's
     
  10. Mr.Pozitiv Well-Known Member

    Plaquenil hydroxychloroquine sulfate dosing, indications. Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration.

    Plaquenil hydroxychloroquine sulfate dose, indications.