It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Maralone vs doxycycline vs chloroquine Hydroxychloroquine 200mg equivalent What are the possible side effects of antimalarial drugs? Plaquenil is most often well-tolerated but, like with any drug, side effects are possible. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time. Hi Everyone, I'm 34 years old and was diagnosed with RA in August of last year and was put on Hydroxychloroquine Plaquenil. I still get some swelling and joint pain in various joints and so my Rheumatologist wanted me to start taking Leflunomide as well, which I've decided against given all the horrible potential side effects which I see some of you have experienced. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil side effects depression Plaquenil Side Effects Common, Severe, Long Term -, Depression and Hydroxychloroquine rheumatoid Chloroquine mice scratchingExpired chloroquine SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil Hydroxychloroquine Sulfate - Sanofi. Common and Rare Side Effects for Plaquenil Oral. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. Just thought I'd drop a line to sympathise with the plaquenil side-effects. I was fore warned about the possible side-effects, but that did not help much when I too had to FLY to the lavatory very quickly on many ocassions during the first 4 - 6 weeks I THINK that's how long it was - can't remember now because I no longer have ANY side effects at all. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects.