It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine ifn signature Does plaquenil reduce fevers Find information about common, infrequent and rare side effects of Plaquenil Oral. She presented 3 months later with multiple skin lesions predominantly on her neck, bilateral forearms, and dorsal feet. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology. Summary Skin discoloration - bluish is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old also take medication Budesonide, and have Pain. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine and skin discoloration Plaquenil & skin discoloration -, Hydroxychloroquine-induced Hyperpigmentation of the Skin. Plaquenil treatment for scleroderma Improvement of the hyperpigmentation a few months after hydroxychloroquine is stopped has been reported, but complete clearance is rare.1 Cautious use of the Q-switched ruby laser has shown promise in the treatment of nonmelanotic hyperpigmentation in limited case reports.5 Our patient’s skin discoloration partially resolved four months after. Hydroxychloroquine-related skin discoloration CMAJ. Hydroxychloroquine sulfate and Skin discoloration - bluish.. Hydroxychloroquine and skin darkening Hi All. - LUPUS UK. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female case 1 and a 78-year-old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4-5 years. Skin discoloration • Hair discoloration • Hair loss • Nausea • Vomiting • Abdominal pain. Other side effects of this drug Talk with your doctor right away if you have any of these signs of • Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.