She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil and mosquito bites Will i lose all of my hair when taking plaquenil Sep 01, 2018 Over time, or with continued IV drug abuse, these deposits can lead to complications, such as retinal artery occlusion, neovascularization and vitreous hemorrhage, all of which can cause severe progressive vision loss. On SD-OCT, the crystalline deposits are observed as hyperreflective dots in the inner retina that distribute along the arteries. Patients suspected of developing retinal toxicity should discontinue chloroquine therapy if possible and undergo further evaluation to confirm toxicity. Take-home points. Patients started on chloroquine or hydroxychloroquine for systemic inflammation are at low but real risk of retinal toxicity from these medications. Jan 01, 2011 SriniVas Sadda, MD, is associate professor of ophthalmology at the Keck School of Medicine of the University of Southern California and the Doheny Eye is Director of the Medical Retina Unit, Ophthalmic Imaging Unit, Retinal Transplantation Laboratory and Digital Image Reading Center. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Retinal deposits plaquenil infared imaging Revised Recommendations on Screening for Chloroquine and., Spotlight Case Chloroquine - The American Society of Retina. Why take plaquenil with foodPlaquenil medicine side effects Large iron containing chronic intraocular foreign body with extensive siderosis of retina. The optic nerve is just to left of foreign body with extensive sheathing of retinal vessels. Imaging device Zeiss FF4. Condition/keywords intraocular foreign body, penetrating trauma, siderosis, trauma Miscellaneous - Retina Image Bank. Fundus Autofluoresence Imaging Principles and Applications. H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS. Although optic nerve and retinal imaging devices have been used to document the appearance of the optic nerve head and retina, there is a lack of evidence from prospective clinical studies demonstrating that clinical outcomes are improved by incorporating this technology into glaucoma screening. Conversely, in both normal adults and patients, we found many thickened structures that were undetect- able in visible wavelength light. To improve imaging of sub-retinal structures, we used infrared light, which passed readily into and out of the deeper fundus layers, with little visual consequence or pupil constriction Wyszecki & Stiles, 1982b. Purpose To investigate the choroidal changes that occur in hydroxychloroquine HCQ retinopathy using multimodal imaging including fluorescein angiography, indocyanine green angiography, and optical coherence tomography OCT angiography and to correlate these changes with retinal findings obtained using OCT and fundus autofluorescence.