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    Tadalafil is for the treatment of adult men with erectile dysfunction, or for men with urinary symptoms due to an enlarged prostate. When you collect your prescriptions, check the brand and strength of the tablets. If the appearance is not the same as usual, speak with your doctor or pharmacist. Erectile dysfunction (sometimes called impotence) means that you cannot get or maintain a proper erection. There are several causes, the most common being due to a narrowing of the arteries that take blood to the penis. Tadalafil works by preventing the action of a chemical in your body, called phosphodiesterase type 5. This helps to relax (widen) blood vessels and improves the flow of blood to the penis following sexual stimulation. Tadalafil is available on prescription, but it is only prescribed on the NHS for men with erectile dysfunction resulting from certain medical conditions. metoprolol 5mg -kə, and Tadacip for the treatment of pulmonary arterial hypertension. It initially was developed by the biotechnology company ICOS, and then again developed and marketed worldwide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Food and Drug Administration (FDA) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction when the conditions coincide. Cialis tablets, in 2.5 mg, 5 mg, 10 mg, and 20 mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20 mg tablets) once per day (OD). On November 21, 2003 the FDA approved tadalafil (as Cialis) for sale in the United States as the third ED prescription drug pill (after sildenafil citrate (Viagra) and vardenafil (Levitra)). Like sildenafil and vardenafil, tadalafil is recommended as an 'as needed' medication. Tadalafil was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is under regulatory review in other regions for this condition. In late November 2008, Eli Lilly sold the exclusive rights to commercialize tadalafil for pulmonary arterial hypertension in the United States to United Therapeutics for an upfront payment of $150 million.

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    This leaflet answers some common questions about CIALIS. It does not take the place of talking to your doctor or pharmacist. Your doctor has weighed the risks of you taking CIALIS against the benefits they expect it will have for you. Your doctor may have prescribed you CIALIS to treat either, or both of these conditions. If you have any concerns about taking this medicine, talk to your doctor or pharmacist. Ask your doctor if you have any questions about why CIALIS has been prescribed for you. Your doctor may have prescribed it for another reason. CIALIS is available only with a doctor's prescription. CIALIS is not intended for use by women, or by children under the age of 18 years. The active ingredient in CIALIS tablets, tadalafil, belongs to a group of medicines called phosphodiesterase type 5 inhibitors. Do not take CIALIS if you are currently taking any nitrates or amyl nitrite. Cialis tablets contain the active ingredient tadalafil, which is a type of medicine called a phosphodiesterase type 5 inhibitor. If you suffer from erectile dysfunction, tadalafil helps you to achieve and maintain an erection by helping more blood get into your penis when you are sexually aroused. An erection is produced via a complex chain of events, involving signals from the nervous system and the release of chemical messengers within the tissues of the penis. One of the messengers released when you're aroused is called cyclic GMP. Cyclic GMP relaxes and widens the blood vessels in the penis, allowing more blood to enter. Cyclic GMP is normally broken down by an enzyme in the body called phosphodiesterase type 5 (PDE5). Tadalafil works by stopping this enzyme from breaking down the cyclic GMP. This allows the blood vessels in the penis to stay dilated for longer, which improves blood flow to the penis and helps produce and maintain an erection.

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